A new feature is a boss-like enemy: the Nemesis, an experimental Tyrant model programmed by Umbrella to hunt down and kill S.T.A.R.S. members. Nemesis is very different from most enemies. He can run, use weapons, and has a dodge move, and is the first monster capable of pursuing the player from one area to the next. Nemesis is encountered throughout the game, in set-pieces, boss fights, and the occasional random encounter as the player explores the city. Even if defeated in combat, Nemesis will eventually get back up and continue the pursuit.
In a departure from the game's predecessors, the player cannot choose between two playable characters from the beginning. Instead, the game is played almost entirely as Jill, although there is a short section in which the player controls Carlos.
Resident Evil 3 incorporates a dodge move that allows the player to avoid or repel enemy attacks. The player can also use a new quick turn ability, spinning 180 degrees, allowing the player to escape or turn to face an enemy very quickly. Enemies can now follow the player up or down stairs.
The game also features an ammunition creation system in which new ammunition can be created from gunpowder through the cartridge reloading tool, or by combining gunpowder with ammunition. Players can also shoot oil drums or pipes located in certain areas resulting in an explosion or a spray of steam that can kill nearby enemies. The game also incorporates a randomization feature in which item and enemy placement, as well as puzzle solutions and cutscenes, change during gameplay...